The portal is the only remnant of the Protestant hospital founded by Barthélémy Ranson and his wife Elisabeth Judith Seignette in 1765 to save their ageing or sick co-religionists from the pressures experienced in the general hospital. The building located in the new city comprised two houses and a large garden used as a cemetery. It was financed by donations of the Reformed Community.
On 24 March 1794 the Protestant hospital was attached to the general hospital by a municipal decision, but granted separate existence on 16 fructidor year XIII -3 September 1805. The hospital eventually disappeared during the mid 20th century.